Thrombophilia and Pregnancy

Abstract Leading cause of death in pregnant women still remains venous thromboembolism, with an incidence 1.4 to 4.9 per 100,000 pregnancies. A special group inherited and acquired coagulation disorders associated a susceptibility thrombosis is thrombophilia. Physiological changes during the pregnancy also contribute occurrence thromboembolic diseases (VTE) pregnancy. Total rate thromboembolism 100 pregnancies 200 births. Etiopathogenesis obstetric complications thrombophilia not clearly defined, which one reasons for occasional failure therapy. In hereditary oxidative stress considered be complications, similar preeclampsia. Based on findings so far, additional research should clarify questions regarding anticoagulants role loss prevention. this paper, we analyze effect screening outcomes, consider justification use anticoagulation therapy difficult situations, discuss about previous knowledge field argue new specific protocols. short, address prescribing evaluation their within therapeutic strategies.